Journal of Anaesthesiology Clinical Pharmacology

ORIGINAL ARTICLE
Year
: 2014  |  Volume : 30  |  Issue : 4  |  Page : 496--501

Comparison of computer-integrated patient-controlled epidural analgesia with no initial basal infusion versus moderate basal infusion for labor and delivery : A randomized controlled trial


Ban Leong Sng1, David Woo2, Wan Ling Leong2, Hao Wang4, Pryseley Nkouibert Assam3, Alex TH Sia1 
1 Department of Women's Anaesthesia, KK Women's and Children's Hospital; Anesthesiology Program, Duke-NUS Graduate Medical School, Singapore Clinical Research Institute, Singapore
2 Department of Women's Anaesthesia, KK Women's and Children's Hospital, Singapore
3 Centre for Quantitative Medicine, Duke-NUS Graduate Medical School; Singapore Clinical Research Institute, Singapore

Correspondence Address:
Ban Leong Sng
Department of Women«SQ»s Anaesthesia, KK Women«SQ»s and Children«SQ»s Hospital, 100 Bukit Timah Road, Singapore - 229 899
Singapore

Background and Aims: Computer-integrated patient-controlled epidural analgesia (CIPCEA) is a novel epidural drug delivery system. It automatically adjusts the basal infusion based on the individual«SQ»s need for analgesia as labor progresses. Materials and Methods: This study compared the time-weighted local anesthetic (LA) consumption by comparing parturients using CIPCEA with no initial basal infusion (CIPCEA0) with CIPCEA with initial moderate basal infusion of 5 ml/H (CIPCEA5). We recruited 76 subjects after ethics approval. The computer integration of CIPCEA titrate the basal infusion to 5, 10, 15, or 20 ml/H if the parturient required respectively, one, two, three, or four patient demands in the previous hour. The basal infusion reduced by 5 ml/H if there was no demand in the previous hour. The sample size was calculated to show equivalence in LA consumption. Results: The time-weighted LA consumption between both groups were similar with CIPCEA0 group (mean [standard deviation (SD)] 8.9 [3.5] mg/H) compared to the CIPCEA5 group (mean [SD] 9.9 [3.5] mg/H), P = 0.080. Both groups had a similar incidence of breakthrough pain, duration of the second stage, mode of delivery, and patient satisfaction. However, more subjects in the CIPCEA0 group required patient self-bolus. There were no differences in fetal outcomes. Discussion: Both CIPCEA regimens had similar time-weighted LA consumption and initial moderate basal infusion with CIPCEA may not be required.


How to cite this article:
Sng BL, Woo D, Leong WL, Wang H, Assam PN, Sia AT. Comparison of computer-integrated patient-controlled epidural analgesia with no initial basal infusion versus moderate basal infusion for labor and delivery : A randomized controlled trial.J Anaesthesiol Clin Pharmacol 2014;30:496-501


How to cite this URL:
Sng BL, Woo D, Leong WL, Wang H, Assam PN, Sia AT. Comparison of computer-integrated patient-controlled epidural analgesia with no initial basal infusion versus moderate basal infusion for labor and delivery : A randomized controlled trial. J Anaesthesiol Clin Pharmacol [serial online] 2014 [cited 2021 Mar 3 ];30:496-501
Available from: https://www.joacp.org/article.asp?issn=0970-9185;year=2014;volume=30;issue=4;spage=496;epage=501;aulast=Sng;type=0