Journal of Anaesthesiology Clinical Pharmacology

ORIGINAL ARTICLE
Year
: 2014  |  Volume : 30  |  Issue : 3  |  Page : 391--396

Analgesic efficacy of transversus abdominis plane block in providing effective perioperative analgesia in patients undergoing total abdominal hysterectomy: A randomized controlled trial


Sulagna Bhattacharjee1, Manjushree Ray2, Tapas Ghose3, Souvik Maitra1, Amitava Layek4 
1 Departments of Anaesthesiology and Intensive Care, All India Institute of Medical Sciences, New Delhi, India
2 Principal, Burdwan Medical College, Burdwan, India
3 Department of GI Anaesthesiology, School of Digestive and Liver Disease, Institute of Post Graduate Medical Education and Research, Kolkata, India
4 Department of Anaesthesiology, CNBC, New Delhi, India

Correspondence Address:
Sulagna Bhattacharjee
Department of Anaesthesiology & Intensive Care, All India Institute of Medical Sciences, Ansari Nagar, New Delhi - 110 029
India

Background and Aims: Transversus abdominis plane (TAP) block has been shown to provide postoperative pain relief following various abdominal and inguinal surgeries, but few studies have evaluated its analgesic efficacy for intraoperative analgesia. We evaluated the efficacy of TAP block in providing effective perioperative analgesia in total abdominal hysterectomy in a randomized double-blind controlled clinical trial. Materials and Methods: A total of 90 adult female patients American Society of Anesthesiologists physical status I or II were randomized to Group B (n = 45) receiving TAP block with 0.25% bupivacaine and Group N (n = 45) with normal saline followed by general anesthesia. Hemodynamic responses to surgical incision and intraoperative fentanyl consumption were noted. Visual analog scale (VAS) scores were assessed on the emergence, at 1, 2, 3, 4, 5, 6 and 24 h. Time to first rescue analgesic (when VAS ≥4 cm or on demand), duration of postoperative analgesia, incidence of postoperative nausea-vomiting were also noted. Results: Pulse rate (95.9 ± 11.2 bpm vs. 102.9 ± 8.8 bpm, P = 0.001) systolic and diastolic BP were significantly higher in Group N. Median intraoperative fentanyl requirement was significantly higher in Group N (81 mcg vs. 114 mcg, P = 0.000). VAS scores on emergence at rest (median VAS 3 mm vs 27 mm), with activity (median 8 mm vs. 35 mm) were significantly lower in Group B. Median duration of analgesia was significantly higher in Group B (290 min vs. 16 min, P = 0.000). No complication or opioid related side effect attributed to TAP block were noted in any patient. Conclusion: Preincisional TAP block decreases intraoperative fentanyl requirements, prevents hemodynamic responses to surgical stimuli and provides effective postoperative analgesia.


How to cite this article:
Bhattacharjee S, Ray M, Ghose T, Maitra S, Layek A. Analgesic efficacy of transversus abdominis plane block in providing effective perioperative analgesia in patients undergoing total abdominal hysterectomy: A randomized controlled trial.J Anaesthesiol Clin Pharmacol 2014;30:391-396


How to cite this URL:
Bhattacharjee S, Ray M, Ghose T, Maitra S, Layek A. Analgesic efficacy of transversus abdominis plane block in providing effective perioperative analgesia in patients undergoing total abdominal hysterectomy: A randomized controlled trial. J Anaesthesiol Clin Pharmacol [serial online] 2014 [cited 2021 Jan 20 ];30:391-396
Available from: https://www.joacp.org/article.asp?issn=0970-9185;year=2014;volume=30;issue=3;spage=391;epage=396;aulast=Bhattacharjee;type=0