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RSACP wishes to inform that it shall be discontinuing the dispatch of print copy of JOACP to it's Life members. The print copy of JOACP will be posted only to those life members who send us a written confirmation for continuation of print copy.
Kindly email your affirmation for print copies to [email protected] preferably by 30th June 2019.

Year : 2019  |  Volume : 35  |  Issue : 4  |  Page : 453-459

Changes in stroke volume during an alveolar recruitment maneuvers through a stepwise increase in positive end expiratory pressure and transient continuous positive airway pressure in anesthetized patients. A prospective observational pilot study

1 Department of Anaesthesia and Intensive Care Medicine, Caen University Hospital, Avenue de la Cote de Nacre, CS 30001; EA 4650, Caen Normandy University, Unicaen, Esplanade de la Paix, CS 14 032, F-14000 Caen, France
2 Department of Anaesthesia and Intensive Care Medicine, Caen University Hospital, Avenue de la Cote de Nacre, CS 30001, F-14000 Caen, France

Correspondence Address:
Dr Jean Luc Hanouz
Service d'Anesthésie Réanimation, CHU de Caen, Avenue Côte de Nacre, CS 30001, 14033 Caen Cedex 9
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/joacp.JOACP_167_18

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Background and Aims: Recruitment maneuvers may be used during anesthesia as part of perioperative protective ventilation strategy. However, the hemodynamic effect of recruitment maneuvers remain poorly documented in this setting. Material and Methods: This was a prospective observational study performed in operating theatre including patients scheduled for major vascular surgery. Patients were monitored with invasive arterial pressure and esophageal doppler. After induction of general anesthesia, before surgery began, preload optimization based on stroke volume (SV) variation following fluid challenge was performed. Then, an alveolar recruitment maneuver (ARM) through stepwise increase in positive end expiratory pressure (PEEP) or continuous positive airway pressure (CPAP) was performed. Hemodynamic data were noted before, during, and after the alveolar recruitment maneuver. Results: ARM through stepwise increase in PEEP and CPAP were applied in 22 and 14 preload independent patients, respectively. Relative changes in SV during ARMs were significantly greater in the ARMCPAPgroup (-39 ± 20%) as compared to the ARMPEEPgroup (-15 ± 22%; P= 0.002). The difference (95% CI) in relative decrease in SV between ARMCPAPand ARMPEEPgroups was -24% (-38 to -9; P= 0.001). Changes in arterial pressure, cardiac index, pulse pressure variation, peak velocity, and corrected flow time measures were not different between groups. Conclusion: During anesthesia, in preload independent patients, ARMs through CPAP resulted in a significantly greater decrease in SV than stepwise increase in PEEP. During anesthesia, ARM should be used cautiously.

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